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Description
CD49B Recombinant Rat mAb (S-1969-12)Product Specification Host Rat Antigen CD49B Synonyms Integrin alpha 2; CD49 antigen like family member B; Collagen receptor; Platelet membrane glycoprotein Ia (GPIa); VLA 2 subunit alpha; ITGA2 Immunogen Recombinant Protein Location Membrane Accession P17301 Clone Number S 1969 12 Antibody Type Rat mAb Application WB Reactivity Hu, Ms Positive Sample A431, mouse spleen Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rat |
| Antigen | CD49B |
| Synonyms | Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia (GPIa); VLA-2 subunit alpha; ITGA2 |
| Immunogen | Recombinant Protein |
| Location | Membrane |
| Accession | P17301 |
| Clone Number | S-1969-12 |
| Antibody Type | Rat mAb |
| Application | WB |
| Reactivity | Hu, Ms |
| Positive Sample | A431, mouse spleen |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
Background
CD49b, also known as the integrin alpha-2 subunit (ITGA2), is a transmembrane glycoprotein that primarily associates with CD29 (integrin beta-1) to form the VLA-2 complex, serving as a key cell surface receptor for collagen and laminin. Widely expressed on platelets, epithelial cells, fibroblasts, and specific immune subsets such as NK cells and T cells, it plays a central role in mediating cell adhesion, migration, signal transduction, and platelet activation; furthermore, it is deeply involved in pathological processes including tissue repair, angiogenesis, and tumor metastasis, acting as a critical bridge connecting the extracellular matrix to the intracellular cytoskeleton.
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Exchange/Return Notes
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