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Description
Claudin 3+Claudin 9 Recombinant Rabbit mAb, PBS Only (SDT-1452-69)Product Specification Host Rabbit Antigen Claudin 9 Synonyms CLDN9 Immunogen Synthetic Peptide Location Cell membrane Accession O95484 Clone Number SDT 1452 69 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF, ICFCM Reactivity Hu Predicted Reactivity Ms Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | Claudin 9 |
| Synonyms | CLDN9 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | O95484 |
| Clone Number | SDT-1452-69 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IF, ICFCM |
| Reactivity | Hu |
| Predicted Reactivity | Ms |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 | |
| ICC | 1:100 | |
| IF | 1:200 | |
| ICFCM | 1:50 |
Background
Claudin-9 is a protein that is part of the claudin family, which plays a crucial role in forming tight junctions (TJs) in epithelial and endothelial cells. Tight junctions are essential for maintaining the barrier function of cell sheets, regulating the paracellular transport of molecules, and providing a scaffold for signaling molecules. Claudin-9 has been implicated in various cancers. It is expressed in several types of tumors and is associated with poor prognosis in gastric cancer. It is also linked to the glycolytic levels in endometrial and esophageal adenocarcinomas and is being investigated for its potential as a therapeutic target in cancer treatment.
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