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Description
Neutrophil Elastase (ELA2) Recombinant Rabbit mAb (S-3766-3)Product Specification Host Rabbit Antigen Neutrophil Elastase (ELA2) Synonyms Elastase 2; Leukocyte elastase; Ela2; Elane Immunogen Synthetic Peptide Location Cytoplasm Accession Q3UP87 Clone Number S 3766 3 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Ms Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | Neutrophil Elastase (ELA2) |
| Synonyms | Elastase-2; Leukocyte elastase; Ela2; Elane |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | Q3UP87 |
| Clone Number | S-3766-3 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Ms |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | Ms |
Background
Neutrophil elastase is a serine protease stored in azurophilic granules of neutrophils, released during inflammation to degrade extracellular matrix components including elastin, collagen, and fibronectin. While essential for immune defense against pathogens, dysregulated activity contributes to tissue destruction in chronic inflammatory diseases such as chronic obstructive pulmonary disease (COPD), cystic fibrosis, and acute respiratory distress syndrome (ARDS). It also modulates inflammatory signaling by processing cytokines and chemokines, making it a therapeutic target for inflammatory and autoimmune conditions.
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Exchange/Return Notes
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