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Description
Alexa Fluor® 488 Rat Anti-Mouse CD223 Antibody (S-R624)Product Specification Host Rat Antigen CD223 Synonyms Lymphocyte activation gene 3 protein; LAG 3; Activation induced cytidine deaminase linked autoimmunity protein (Aida); Lag3 Location Cell membrane Accession Q61790 Clone Number S R624 Antibody Type Rat mAb Isotype IgG1,k Application FCM Reactivity Ms Positive Sample mouse CD3, CD28 antibody treated C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488
Product Specification
| Host | Rat |
| Antigen | CD223 |
| Synonyms | Lymphocyte activation gene 3 protein; LAG-3; Activation-induced cytidine deaminase-linked autoimmunity protein (Aida); Lag3 |
| Location | Cell membrane |
| Accession | Q61790 |
| Clone Number | S-R624 |
| Antibody Type | Rat mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | mouse CD3, CD28 antibody treated C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Ms |
Background
CD223, also known as LAG-3 (lymphocyte activation gene-3), is a type I transmembrane protein belonging to the immunoglobulin (Ig) superfamily. It is expressed on the surface of activated T cells, regulatory T cells (Tregs), natural killer (NK) cells, and some other immune cells. Structurally, it is similar to CD4 and has a higher binding affinity to MHC class II molecules than CD4. LAG-3 primarily functions as an immune checkpoint receptor, negatively regulating T-cell activation, proliferation, and cytokine production. In cancer and chronic infections, elevated LAG-3 expression is associated with T cell exhaustion, limiting anti-tumor and antiviral responses. Due to its significant role in immune regulation, LAG-3 has become a promising target for cancer immunotherapy and the treatment of autoimmune disorders.
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4.6 ★★★★★
Based on 6 reviews
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Product Reviews
★★★★★ 5
Inexpensive walls.
Color: Grey, Size: 34" - 3 Panel, Color: Grey, Size: 34" - 3 Panel
We had a hot request for a workstation in the warehouse with some privacy.
These have worked great. Easy to assemble. They are lightweight and stable.
This was an inexpensive solution that looks professional. Our client loved it.
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Reviewed in the United States on August 1, 2025
★★★★★ 1
Dont wait! Assemble right away! Just in case you need to return it.
Color: Black, Size: 22" - 4 Panel
Ok, I like the idea of this but the assembly is frustrating. One side lined up perfectly with the holes however, the small bars that connect the screen to base is not lining up. I think it's do the fabric the screen or divider is made of. It's not stretchy. I brought this months ago and just opened it today. I'm upset and don't even think returning it is possible. If the material was a bit longer or stretchy to give a little room to work with this divider would be great. However, I'm not sure what I can use it for since I'm unable to attach it to the bottom. Beware! Don't wait like me. Tip for the manufacturer. Next time invest in Velcro dividers so the fabric can be adjusted with ease. Literally if I take the screen off the frame aligns perfectly. However, it defeats its purpose of privacy. I might buy some material myself and create a more flexible divider. Or I'll buy Velcro myself and attach to the bottom. I don't know yet.
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Reviewed in the United States on December 15, 2025
★★★★★ 5
Very practical and so far its working great.
This outlet extender is super practical! I installed it just behind a night stand to extend the outlet above it.
The built in USB C ports can fast charge a Samsung S25 on a MagSafe base, so they are at least good for 15W.
The outlet came disassembled and very well packed. There are 3 extensions included to change the reach of the outlet, but for a nightstand, a single extension was all that is needed.
The outlets on the extender are nice and tight and like mentioned before, the USB ports work well and are very convenient to have.
There is also an On/Off switch at the top of the extender you can use to turn off all the devices connected to it.
Overall a great kit, that seems well made and should hopefully last a long time. So far I can recommend it.
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Reviewed in the United States on June 1, 2026
★★★★★ 5
Finally, a smart solution for that impossible outlet behind the couch
I have one specific outlet in my living room that drives me absolutely crazy. It’s directly behind our heavy sectional sofa, and every time I need to plug in a laptop charger or the vacuum, I have to literally wrestle the furniture away from the wall and blindly reach down into the dark. When I saw this TROND extendable outlet stick, I bought it immediately hoping it would solve that exact headache. It totally did.
The design is brilliant. It’s modular, so you can adjust the length anywhere from 16 to 39 inches depending on how many segments you screw together. I used all three pieces so the actual power strip sits right at the perfect height just above the back of the couch. Now I have five outlets and two USB-C ports right where I can actually reach them. The USB-C ports charge my phone quickly, and having built-in surge protection gives me peace of mind for my electronics. Plus, the 360-degree rotating plug lies completely flat, so the couch can push all the way back against the wall without bending any cords.
I did run into one quirky issue when installing it, which I took a couple of photos of to show you. In the US, our wall outlets are usually installed with the round ground prong on the bottom. However, the plug on this device is oriented with the ground prong on the top. If you plug it into a standard outlet, the cord wants to run upwards instead of down.
Fortunately, it’s an incredibly easy DIY fix. I just went to my breaker box, shut off the power to the living room, unscrewed the wall outlet, flipped it upside down so the ground prong was on top, and screwed it back in. It took less than five minutes and completely solved the problem.
Even with that minor orientation quirk, this thing is a total game-changer for awkward living room layouts. If you're tired of scraping your knuckles trying to reach behind furniture, this is worth every penny.
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Reviewed in the United States on June 2, 2026
★★★★★ 5
Perfect kitchen wall outlet
Size: 3 FT, Size: 3 FT
This is the perfect solution for a kitchen wall outlet that is plugged into the unused second socket behind the refrigerator. Now I can leave my blender and food processor on the small countertop next to my refrigerator. So convenient! And also a good spot to charge my cell phone.
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Reviewed in the United States on April 29, 2026
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