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Description
Rat Anti-Mouse CD182 Antibody (S-R718)Product Specification Host Rat Antigen CD182 Synonyms C X C chemokine receptor type 2; CXC R2; CXCR 2; GRO MGSA receptor; High affinity interleukin 8 receptor B (IL 8R B); Cmkar2; Gpcr16; Il8rb; Cxcr2 Location Cell membrane Accession P35343 Clone Number S R718 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse bone marrow Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rat |
| Antigen | CD182 |
| Synonyms | C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B (IL-8R B); Cmkar2; Gpcr16; Il8rb; Cxcr2 |
| Location | Cell membrane |
| Accession | P35343 |
| Clone Number | S-R718 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse bone marrow |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:200 | Ms |
Background
CD182, also known as CXCR2 or IL-8 receptor beta, is a 67-70 kDa member of the G-protein-coupled receptor family with seven transmembrane regions. It is expressed on various cell types, including neutrophils, natural killer cells, T cell subsets, monocytes, endothelial cells, and others. CD182 plays a crucial role in mediating chemotaxis, cell activation, proliferation, and angiogenesis. It binds to chemokines such as IL-8, NAP-2, GCP-2, and GRO-alpha, -beta, and -gamma, which induce these biological effects. This receptor is also involved in neutrophil migration to sites of inflammation and is essential for the positioning of oligodendrocyte precursors in the developing spinal cord.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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