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Description
IL-17F Protein, HumanProduct Specification Species Human Synonyms Interleukin 17F; IL 17F; Cytokine ML 1; Accession Q96PD4 Amino Acid Sequence Arg31 Gln163, with C terminal His Tag Expression System HEK293 Molecular Weight 20 22 kDa (Reducing) Purity >95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Species | Human |
| Synonyms | Interleukin-17F; IL-17F; Cytokine ML-1; |
| Accession | Q96PD4 |
| Amino Acid Sequence | Arg31-Gln163, with C-terminal His Tag |
| Expression System | HEK293 |
| Molecular Weight | 20-22 kDa (Reducing) |
| Purity | >95% by SDS-PAGE and HPLC. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | ·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Cytokine. 2009 Apr;46(1):7-11. Epub 2009 Feb 23. |
Background
Interleukin-17F (IL-17F) is a member of the interleukin-17 cytokine family that plays a key role in regulating inflammatory responses and immune reactions. IL-17F is primarily produced by activated T cells, particularly Th17 cells, and acts on various cell types, including epithelial cells, fibroblasts, and immune cells. IL-17F is involved in the pathogenesis of inflammatory and autoimmune diseases, such as asthma, rheumatoid arthritis, and inflammatory bowel disease. It promotes the production of pro-inflammatory cytokines and chemokines, leading to recruitment of immune cells to sites of inflammation and tissue damage.
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