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Description
RON/CD136 His Tag Protein, HumanProduct Specification Species Human Synonyms RON, CD136, MSP R, MSP receptor, MSPR, MST1R Accession Q04912 Amino Acid Sequence Glu25 Leu571, with C terminal 10*His
Product Specification
| Species | Human |
| Synonyms | RON, CD136, MSP R, MSP receptor, MSPR, MST1R |
| Accession | Q04912 |
| Amino Acid Sequence | Glu25-Leu571, with C-terminal 10*His EDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVTYEGDRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGDPGCQTCAACGPGPHGPPGDTDTKVLVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVALSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSFCPNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAHMGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLGDHLLFASGDQVFQVPIQGPGCRHFLTCGRCLRAWHFMGCGWCGNMCGQQKECPGSWQQDHCPPKLGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 35-43&73-80kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Mallakin A. et al. (2006) Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury. Am J Respir Cell Mol Biol. 34(1): 15-27. 2、Welm A L. et al. (2007) The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans. Proc Natl Acad Sci U S A. 104(18): 7570-5. |
Background
RON is a receptor tyrosine kinase (RTK) of the MET receptor family that is canonically involved in mediating growth and inflammatory signaling. This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. It had been shown that MST1R/CD136 plays a critical role in Ni-induced lung injury in mice. The overexpression of MSP, MT-SP1, and MST1R was a strong independent indicator of both metastasis and death in human breast cancer patients and significantly increased the accuracy of an existing gene expression signature for poor prognosis.
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4.2 ★★★★★
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Product Reviews
★★★★★ 5
It works
Fits great and holes the phone secure, I would recommend this product.
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Reviewed in the United States on June 22, 2025
★★★★★ 4
Holds the phone very securely
A little on the expensive side but it really holds the phone well. Much better than the vent clamp I was using.
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Reviewed in the United States on June 1, 2026
★★★★★ 4
Good, but...
The item is good and works well but it blocks the camera display.
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Reviewed in the United States on June 29, 2025
★★★★★ 5
Perfect fit for Kia Carnival
Color: for Kia Carnival 2022-2024, Color: for Kia Carnival 2022-2024
The designer of this van made it difficult to find a good solution for phone mount. I tried 4 different mounts until this, and it's perfect. The only problem is the holder itself- it's kinda crappy. The good news is that the mount uses standard sized ball joints so I took an old magnetic mount and mated to this, perfect phone mount.
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Reviewed in the United States on December 9, 2023
★★★★★ 1
2024 Kia Carnival SX Prestige
Color: for Kia Carnival 2022-2024
Does not fit this vehicle. The little tabs that are supposed to click in aren't long enough. Returning.
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Reviewed in the United States on September 13, 2024