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Description
Angiopoietin-1(277-498) His Tag Protein, MouseProduct Specification Species Mouse Synonyms Angiopoietin 1, AGP1, AGPT, Ang1, ANG 1, ANGPT1 Accession O08538 Amino Acid Sequence Arg277 Phe498, with C terminal His Expression System HEK293 Molecular Weight 28 33kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after
Product Specification
| Species | Mouse |
| Synonyms | Angiopoietin-1, AGP1, AGPT, Ang1, ANG-1, ANGPT1 |
| Accession | O08538 |
| Amino Acid Sequence | Arg277-Phe498, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 28-33kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Yoon J C. et al. (2000) Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol Cell Biol. 20(14): 5343-5349. |
Background
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability.
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4.5 ★★★★★
Based on 13 reviews
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Product Reviews
★★★★★ 3
At least it's beautiful!
Format: Hardcover
Firstly, this book is beautiful to look at. The pages are heavy and glossy, and the artwork is all wonderful. Lots of things from the now defunct Initiates made it into the book, as well as the "conclusion" of the Desmond thread of the Modern Day plot from the comics. It's nice to lay on the coffee table for gamer friends to stare at for a few minutes.
The major problem is the factual errors and editing issues. They're not obvious on first glance, but when you look a second or third time things truly stand out. Things like calling Chrétien Lafrenière one of Germain's allies on [Germain's] his profile page. I won't put all the errors I've found in my review for brevity, but for an item aimed at fans, it's disappointing to find so many of them. And these aren't small/minor details that are wrong. They're major plot points and important details of main story missions.
I'm still a fan of the series and I'm happy to have the book for the art, but I would never suggest it for the content. The fan-run wiki (which is mentioned in the thanks section) is far more accurate and complete.
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Reviewed in the United States on May 24, 2020
★★★★★ 5
Beautiful book and artwork
Format: Hardcover
The book comes within a slip case so it remains undamaged, and the open spine makes it really comfortable to hold and look through. There is a lot of gorgeous artwork of characters' different armor and dye variations, and the landscape works are very moody and atmospheric. There's also a lot of storyboarding, menu mockups, and promo pieces. There is a little too much white space around the images, but at least it keeps the format consistent.
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Reviewed in the United States on January 16, 2025
★★★★★ 5
Beautiful Book with Surprising Extra Details
Format: Hardcover
If you, or someone you know, is a fan of this game there will be no disappointment in this purchase.
I bought 3 different 'Game Art' books for 3 of my nephews this Christmas and this one far surpassed the others in detail and overall unboxing experience. The extra sleeve of the book along with the Japanese style spine binding are just some of the details that set this one apart. You can tell that a lot of the creative passion from the game was translated to this book's aesthetic. This is brand awareness done right!
Note: The other 2 books were for 'Apex Legends & Last of Us 2' and they were great as well, but this one stood out and they were essentially all the same price.
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Reviewed in the United States on December 24, 2023
★★★★★ 5
20/10
Format: Hardcover
Great quality! Worth the price! My favorite PS5 game so far. Hopefully yotei lives up to the hype!
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Reviewed in the United States on July 23, 2025
★★★★★ 5
Beautiful and high quality book, highly recommended for Ghost fans
Format: Hardcover, Format: Hardcover
I pre ordered this the day they went live, knowing I would not be disappointing. I wasn't. The slipcase that comes with it is sturdy and protects the book well. The book itself is quality and has a great spine that lets you set the book down, and will keep the page open without you needing to hold it, which is a common issue with books. The art itself is gorgeous, sometimes spanning pages. There is commentary and notes from 2 great people from SUcker Punch Productions: Jason Connell and Andrew Goldfarb, providing insight in to the development process of Ghost of Tsushima. Much to my surprise, there is even a whole chapter dedicated to the upcoming co-op expansion to the game, Ghost of Tsushima: Legends. I am supremely happy with my purchase.
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Reviewed in the United States on September 2, 2020
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