SKU: 30052384320

Mouse Anti-Human CD200R Antibody (S-3128)

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Description

Mouse Anti-Human CD200R Antibody (S-3128)Product Specification Host Mouse Antigen CD200R Synonyms Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CRTR2; MOX2R; OX2R; CD200R1 Location Cell membrane Accession Q8TD46 Clone Number S 3128 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral blood Leukocyte Purification Protein G Concentration 2 mg ml Conjugation

Product Specification


Host Mouse
Antigen CD200R
Synonyms Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CRTR2; MOX2R; OX2R; CD200R1
Location Cell membrane
Accession Q8TD46
Clone Number S-3128
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample human peripheral blood Leukocyte
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CD200R is a trans-membrane glycoprotein of the immunoglobulin superfamily encoded by CD200R1, expressed chiefly on myeloid cells (macrophages, dendritic cells, microglia) and some lymphoid subsets; when engaged by its ligand CD200 (OX-2) it becomes tyrosine-phosphorylated in its cytoplasmic NPxY motif, recruits the adaptor Dok-2 and RasGAP, thereby dampening Ras/MAPK and NF-κB signaling to suppress production of TNF-α, interferons and iNOS, curb mast-cell degranulation, restrain ILC2 effector cytokines, and broadly down-regulate innate and adaptive inflammatory responses, a signaling axis that is exploited by tumors for immune evasion and is being therapeutically targeted to treat asthma, neuroinflammation and cancer .

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Exchange/Return Notes
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SKU: 30052384320

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4.8 ★★★★★
Based on 26 reviews
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Product Reviews
B
Verified Purchase
BillyD
Boise, US
★★★★★ 5
Very durable and amazingly fun
Pattern Name: Assorted, Size: Pack of 2
My dog loves frisbees, but now this is the only one I’ll ever buy again! If you’ve ever had a dog frisbees you know that some dogs can eat/chew-up a frisbee in literally minutes. Not this one, no way! I’ve bought several of these because I keep one in my truck, one on my boat, one for the backyard, and one just for the dog-park (can you say “community drool”? I take these everywhere (see videos) and every single dog that gets ahold of it loves it. As a matter of fact the only problem I’ve ever had with it is when I take my dog to the dog park all the other dogs fight over this frisbee. As far as quality it’s tough as nails, sure if my dog sat and gnawed on it for hours he might eventually tear it up but it would take a very long time and I would see him chewing it up. My dog and all the other dogs at the dog park will gnaw and chew on it and not one dog (from labs to retrievers to pitbulls to Rottweilers to even a malinois, a German Shepard and a massive cane corso to a little cur of a dog) not one has torn it up, and they ALL play tug of war with it. It’s great for teaching young and old dogs how to catch because it is soft enough not to bounce out of their mouth and they can catch it with a good grip. The best thing ever: it’s malleable and can be easily put back into a round shape even after heavy pulling. It floats on the water perfectly and will not sink no matter how wet with water (or drool!). On top of that it’s very light yet is easy to throw in even heavy wind, and as a frisbee guy for decades when I say it throws good, it’s pretty darn accurate whether wet or dry. Personally I have found I like the pink one the best (not the pink swirly one, even though it’s fine I like the black edging on the others as they seem tougher and more solid for throwing). The solid pink ones are easier to see in water, grass, dirt, etc. I have bought 5 of these so far, not because they get trashed or fall apart, but like I said it’s because I have one for every purpose. Highly recommend the solid pink as best color wise.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 30, 2025
M
Verified Purchase
Michael A Shaffer
Bozeman, US
★★★★★ 4
Great frisbee for our golden doodle
Pattern Name: Assorted, Size: 9" Pack of 5
Love the product. Our golden doodle can chase these all day long. They are light enough and easy on him to catch them and they fly well. Only complaint is I wish they were a little cheaper. He does go through them
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Reviewed in the United States on March 12, 2026
E
Verified Purchase
E. Johnson
Port Orchard, US
★★★★★ 5
Amazing frisbees for dogs!
Pattern Name: Assorted, Size: Pack of 2
These are the best frisbees for dogs. They hold up well but do fade over time if left in the sun. Our border collie mix is an avid frisbee guy and these are his favorite. The float in water well and last for quite a while. He’s not a chewer so I can’t speak to the durability with chewing. I buy a couple every year when his old ones get faded and gross, otherwise we would continue to use these for over a year!
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Reviewed in the United States on April 21, 2026
F
Verified Purchase
Fawn
Carnegie, US
★★★★★ 5
Our dogs adore these!
Pattern Name: Assorted, Size: 9" Pack of 5
We have two large-breed dogs who love retrieving in the water and playing catch in the yard, and these flying discs have been fantastic. They are the perfect size, easy to throw due to their lightweight design, and the vibrant colors make them simple to locate. While they hold up well during play, they are best suited for fetching rather than tug-of-war, as the material can be delicate if pulled too hard. Overall, both we and our dogs absolutely love them!
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Reviewed in the United States on May 28, 2026
H
Verified Purchase
Houston Littlejohn
Phoenix, US
★★★★★ 3
Fun toy, breaks with rough play
Pattern Name: Assorted, Size: Pack of 2
It's a fun toy and my dog loved it, however he is quite rough so the toy broke at the point where the little plastic loop in the frisbee connects. Good for dogs who are a little more gentle.
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Reviewed in the United States on February 17, 2026

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