SKU: 69144307732

SHBG His Tag Protein, Human

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Description

SHBG His Tag Protein, HumanProduct Specification Species Human Accession P04278 Amino Acid Sequence Leu30 His402, with C His tag Expression System HEK293 Molecular Weight Predicted MW: 42. 2 kDa Observed MW: 50 kDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer 0. 2M PBS, pH7. 4. Reconstitution Reconstitute no more than 1 mg mL according to the size in deionized water after rapid

Product Specification


Species Human
Accession P04278
Amino Acid Sequence

Leu30-His402, with C-His tag

Expression System HEK293
Molecular Weight

Predicted MW: 42.2 kDa Observed MW: 50 kDa

Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

0.2M PBS, pH7.4.

Reconstitution

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Stability & Storage


12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to androgens and estrogens. SHBG is found in all vertebrates apart from birds. SHBG inhibits the function of these hormones. Thus, the local bioavailability of sex hormones is influenced by the level of SHBG. SHBG’s production is regulated under the influence of FSH on Sertoli cells, enhanced by insulin, retinol, and testosterone. The relative binding affinity of various sex steroids for SHBG is dihydrotestosterone (DHT) > testosterone > androstenediol > estradiol > estrone. SHBG levels are usually about twice as high in women than in men. In women, SHBG serves to limit exposure to both androgens and estrogens. Low SHBG levels in women have been associated with hyperandrogenism and endometrial cancer due to heightened exposure to androgens and estrogens, respectively. During pregnancy, due to activation of SHBG production in the liver by high estrogen levels, SHBG levels increase by five-fold to ten-fold.
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Exchange/Return Notes
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SKU: 69144307732

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4.7 ★★★★★
Based on 13 reviews
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Verified Purchase
Rena J.
Bozeman, US
★★★★★ 5
This container is perfect
A durable container that will hold a good amount of syringes. Great for home usage.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2026
J
Verified Purchase
James Dieter
Massapequa, US
★★★★★ 5
Nice size for storage.
Size: 5 Quart, Unit Count: 2.0
Nice size for my Lantus pens. The price was very reasonable. Sturdy with a nice locking lid.
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Reviewed in the United States on April 24, 2026
D
Verified Purchase
Dawn E
Whiting, US
★★★★★ 5
Exactly as expected.
Size: 5 Quart, Unit Count: 1.0
Exactly what it is made for. It is a perfect size for months worth of needles that we are using for our peptide injections.
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Reviewed in the United States on May 20, 2026
J
Verified Purchase
Justin Brown
Natrona Heights, US
★★★★★ 4
Works and safe!
Size: 5 Quart, Unit Count: 1.0
Good sharps container. Fits typical diabetic syringes perfectly. It also fits zepbound auto-injection pens, but they are a little more difficult to cram into the opening so I took off a star for that.
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Reviewed in the United States on January 9, 2026
A
Verified Purchase
April Salerno
Birmingham, US
★★★★★ 5
Excellent size
Excellent for prescription needle disposal. The containers provided by my pharmacy are too small and don't hold all of my used prescription supplies. Lid closes easily and keeps everyone safe from accidental insulin injections!
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Reviewed in the United States on April 5, 2026

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